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      首頁 > 產品中心 > 常規生化試劑 > 白細胞介素 > abs04046Recombinant Human Interleukin-15/IL-15

      Recombinant Human Interleukin-15/IL-15

      簡要描述:愛必信特色產品線(全部現貨):
      二抗、標簽抗體、對照抗體;WB相關:ECL發光液、預染marker、預制膠;IHC相關:二抗試劑盒、組化筆;IP/CoIP試劑盒;細胞因子、信號通路調節劑;血清、BSA、蛋白酶K、CTB、TTX、CEE;凋亡試劑盒、呼吸爆發試劑盒;動植物提取物...

      • 產品型號:abs04046
      • 廠商性質:生產廠家
      • 更新時間:2018-03-21
      • 訪  問  量:241

      詳細介紹

      品牌自營品牌規格10ug
      供貨周期一周
      概述
      描述Recombinant Human Interleukin-15 is produced by our E.coli expression system and the target gene encoding Asn49-Ser162 is expressed.
      別名Interleukin-15, IL-15, IL15
      形態Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0.
      來源E.coli
      氨基酸序列NWVNVISDLKKIEDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHDTVEN LIILANNSLSSNGNVTESGCKECEELEEKNIKEFLQSFVHIVQMFINTS
      內毒素水平Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
      Accession #P40933
      性能
      背景Human Interleukin 15 (IL-15) is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL15 receptor (IL-15RA) with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not the alpha subunit of the IL2 receptor. IL-15 is structurally and functionally related to IL-2. Both cytokines share some subunits of receptors, allowing them to compete for and negatively regulate each other's activity. The number of CD8+ memory T cells is controlled by a balance between IL-15 and IL-2. Despite their many overlapping functional properties, IL-2 and IL-15 are, in fact, quite distinct players in the immune system. IL-15 is constitutively expressed by a wide variety of cell types and tissues, including monocytes, macrophages and DCs. Mature Human IL-15 shares 70% amino acid sequence identity with Mouse and Rat IL-15.
      溶解方法Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
      保存方法Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
      純度Greater than 95% as determined by reducing SDS-PAGE. 

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